Biotechnological Innovations in Chemical Synthesis - Open Univ.
KMMS will be a significant addition to the University, with exciting opportunities for education and research in the School of Biosciences. This is a measure of the proportion of staff involved in high-quality research in the university.
Biotechnological Innovations in Chemical Synthesis - Knovel
Please see the University League Tables for more information. The MSc in Biotechnology and Bioengineering involves studying for credits of taught modules, as indicated below. The taught component takes place during the autumn and spring terms. You will undertake a period of advanced training in research, technical and transferable skills with application in the biotechnology and bioprocessing area, including an extended practical training in cutting-edge genome editing.
This training will be harnessed with a range of modules specialising in advanced studies of biotechnology and its application. A credit research project take place over the summer months.
The programme is taught by staff from the Industrial Biotechnology Centre, an interdisciplinary research centre whose aim is to solve complex biological problems using an integrated approach to biotechnology and bioengineering. It is administered by the School of Biosciences who also contribute to the programme. The modules listed below are indicative of those offered on this programme. This list is based on the current curriculum and may change year to year in response to new curriculum developments and innovation.
This module will consider key areas of biotechnology and bioengineering including an introduction to drug discovery and design, systems biology and synthetic biology, gene expression and the engineering of cells to modulate cellular processes, the mechanics of cells from an engineering perspective, industrial biotechnology specifically biofuels and small molecule systems biology , protein and vaccine based drugs, regenerative medicine and bionanomaterials.
This will be delivered through workshops and seminars by specialists within the CMP and involve a number of course work assignments that will consider the most current research and thinking in these areas. This will be complemented by two three day practical's, one on mammalian cell engineering and the other on synthetic biology.
Science has a profound influence on professional practice in the private and public sector. This module considers the ways in which different professions interact with science and scientists, and how this influences the work they do.
Their interaction with the public will also be discussed. A series of speakers with diverse professional backgrounds education, industry, government, policy making, the law, the media will describe their work, the role of science in the profession, and the way in which science influences their actions and interactions with the public and other professions. This will relate to scientific content in a range of scientific contexts, including cancer, reproductive medicine, biotechnology and healthcare.
This will be illustrated by case studies presenting challenges and dilemmas concerning the communication of science in the context of different professions and their target audiences. The module aims to develop understanding and practical skills in molecular biology, based around interactive workshops, practical sessions and group work.
The module will involve practical sessions covering key practical and transferable skills in molecular biology and biotechnology. These will be accompanied by interactive workshops and classes that review the theory of these techniques, and will use case studies to illustrate their impact and importance in both academic and industrial settings. Students will learn skills in experimental design using appropriate case studies that will embed them within the relevant research literature.
They will also gain experience of analysis and statistical interpretation of complex experimental data. This module provides students with critical perspectives upon current and emerging cancer therapies, how they are developed, and how they are applied in the clinical setting. The harnessing of scientific knowledge in the treatment of disease requires a complex series of highly regulated studies that must be performed under highly-regulated legal and ethical frameworks. This module reviews the transition from promising cancer therapy to fully realised therapeutic agent, using specific therapies as examples.
It will also discuss the emerging potential for personalised medicine based on patient-specific molecular biomarkers. This module will consider key areas of analytical technologies used for the analysis of proteins, small molecules and cells. Industrial case studies will be covered to demonstrate how different techniques and approaches are integrated in a commercial environment.
Students will also be expected to design and implement a protocol aim at recovering and characterising a protein molecule from mammalian cell culture within set constraints and parameters.
There will also be a visit to an industrial analytical laboratory to demonstrate such technologies in the work place. This will be complemented by a one week practical where the students are asked to design a process to purify and characterise a molecule and then use this to setup a crystallisation screen. The module aims to develop understanding and analytical skills in order to fully embed students within the culture of cancer research.
Based around seminars and interactive workshops, the initial stages of the module will involve an intensive rotation of seminars covering recent key developments in the field of cancer, delivered by experts, accompanied by critical evaluation and analysis of research articles exploring these research themes. Students will analyse, present and discuss the relevant research literature. They will gain experience in scientific design, literature analysis, scientific communication and the analysis and statistical interpretation of complex experimental data.
The later stages will focus on the students' own extended research project and will involve the preparation of a research proposal. This module is designed to provide students across the university with access to knowledge, skill development and training in the field of entrepreneurship with a special emphasis on developing a business plan in order to exploit identified opportunities.
The module complements students' final year projects in Computing, Law, Biosciences, Electronics, Multimedia, and Drama etc. This module facilitates the development of an entrepreneurial mind-set, and equips students with necessary cutting-edge knowledge and skills vital for generating value in a knowledge based economy. The curriculum will include the following areas of study:. Students will undertake an independent research project that will be designed by the student, in consultation with an academic supervisor, to address specific research questions.
Students will be trained in key techniques relating to the project, and will work independently under the supervisor's guidance to design and execute experiments that will address the questions formulated earlier. The students will spend approximately 14 weeks in the laboratory and with then write up their findings in the style of a scientific report for publication in a high impact factor scientific journal.
They will present a poster and an oral presentation in research symposia arranged by the School. A postgraduate degree in the School of Biosciences is designed to equip our graduates with transferable skills that are highly valued in the workplace. Our research-led ethos ensures that students explore the frontiers of scientific knowledge, and the intensive practical components provide rigorous training in cutting edge technical skills that are used in the modern biosciences while working in areas of world-leading expertise within the School.
Destinations for our graduates include the leading pharmaceutical and biotechnological companies within the UK and leading research institutes both at home and abroad. The School of Biosciences has a dedicated Placements and Employability Officer and your academic supervisor will be able to advise you and give you access to professionals in their network. The University has a friendly Careers and Employability Service, which can give you advice on how to:. This programme has been accredited by the Royal Society of Biology. Masters Accreditation by the Society recognises programmes that support the development of specific skill sets, competencies and training which will enhance life and health science research.
Programmes submitted for accreditation must satisfy the general requirements for Advanced Accreditation, which includes a significant period of practice. The School is well equipped, with excellent general research laboratories, together with a range of specialised research resources including facilities for growing micro-organisms of all kinds, extensive laboratories for animal cell culture and monoclonal antibody production and an imaging suite providing high-resolution laser confocal and electron microscopy. Additionally, the macromolecular analysis facility provides resources for protein and mass spectrometry, CD and fluorescence spectroscopy, surface plasmon resonance, and HPLC and FPLC systems for all aspects of biochemical and microbiological research.
Our NMR spectrometer was upgraded to this status via an equipment research award from the Wellcome Trust. All research students are supervised closely and are regularly monitored online using the University progression and monitoring system. All postgraduate students have access to electronic and other resources providing information regarding technical issues relevant to their degrees, as well as subject-specific and transferable skills training.
All research students are allocated a Postgraduate Supervisory Team, consisting of one or more day-to-day supervisors, and one or more members not involved in day-to-day supervision whose task it is to serve as independent monitors of progress.
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Students on taught programmes are assigned a personal academic tutor to provide additional support in their postgraduate study. Throughout the course, you are fully embedded in the research culture of the School by attending research seminars and careers guidance sessions, and also participating in our vibrant outreach programme within the local community. In addition to taught modules, an in-depth research project takes place during the summer under the guidance of members of academic staff.
These projects benefit from our outstanding research environment and first-class facilities. Every week, Biosciences runs school seminars where external guest speakers or staff, talk about recent research. In addition, the department runs FIREBio Forum for Innovation, Research and Enterprise in Biosciences , which is a weekly informal meeting for staff, postdocs and postgraduates involving short presentations and discussions.
Postgraduates can use the opportunity to present unpublished research findings and discuss them in a supportive environment. It also receives funding on specific projects from a number of industrial organisations and collaborators. Staff publish regularly and widely in journals, conference proceedings and books.
The programme is designed to broaden your understanding of global issues and current affairs as well as to develop personal skills which will enhance your employability.
Minimum 2. Only requires 1 mg and the provider of the compound does not need to provide a structure. The Open Innovation Drug Discovery Screening program offering enables scientists to submit compounds for experimental evaluation in Lilly's proprietary biological assays. Results from the assays inform next steps towards further collaborative work. Once Lilly receives the physical samples, they are routed for biological evaluation in several different assay modules. All biological results are provided to the investigator through their personal OIDD account. The OIDD team may choose to reach out to investigators to discuss next steps for specific compounds with a desirable profile.
The ASL provides synthetic chemists the ability to explore novel synthetic approaches, improve reaction efficiency, and test the feasibility of synthetic routes to maximize the yield of targeted compounds. CSDD staff is here to help Notre Dame researchers utilize Lilly's atomated synthesis lab to prepare unique compounds and explore interesting new chemistry contact us for assistance. We are now a contract research site of roughly 50 employees working in 22, square feet of new lab space.
Our group is focused on in vitro ADME studies, including permeability, metabolic stability, metabolite identification, and drug—drug interaction DDI risk assessment, ranging from highly automated discovery screening platforms to definitive development studies that enable regulatory submission.